Process for the Synthesis of AA-dUTP-Cy3/Cy5- a Novel Fluorescent Labeling Agent
Brief description of the process / product / technology developed: Pax 3 is an important biomarker for NTD in Human beings diagnosed in our preliminary work. When this pax3 is down regulated NTD is predisposed in human beings. This invention relates to the Biomarker PAX3 for the detection of NTD in human mothers.The principal object of the present invention is to provide a detection kit for the prenatal screening of neural tube defect. o Yet another object of the present invention is to provide a detection kit based on the genetic analysis of Pax genes. o Still another object of the present invention is to provide a biomarker for developing the neural tube defect detection kit. o Another object of the present invention is to provide application of detection kit for the screening of neural tube defect in the first trimester of pregnancy. 6. Applications / uses of the process / product / technology (industry, sectors, areas etc.)- Hospitals
Sector: Biotechnology
Country: India
Area of Application: Labeling of RNA and cDNA as hybridization probe in microarray detection
Keywords: Synthesis, AA-dUTP-Cy3/Cy5, AA-dUTP, Cy3/Cy5-NHS, RNA, cDNA
Advantages: A process for the synthesis of flourescent cyanine dye labeled base modified nucleoside triphosphates analogues for the labeling of necleotides as hybridization probe in microarrary detection
Environmental aspects: Bio-Degradable and Environmental Friendly
Development Status: Laboratory Model
Legal Protection: Patent
Technical specifications:
Transfer Terms: Consultancy , Technical Services , Technology Licensing
Target Countries: Chile, China, India, New Zealand, Sri Lanka, United States, United Kingdom
Estimated cost (US$):
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Contact Person: NA
Address: Amity University Uttar Pradesh Sector-125, Noida
City: Distt Gautam Buddha Nagar
Country: India
Zip/Pin Code: 201303