Transdermal Patch for Drug Delivery
The present technology provides a novel steroidal drug delivery system as a transdermal patch useful as contraceptive agent. A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.The drug delivery system in the present technology is comprised of a matrix layer which is composed of an effective amount of steroidal drug, polymers and pharmaceutically acceptable excipients. In development of Transdermal Drug Delivery System (TDDS) patch, several polymers were used in different concentrations and dissolved with suitable solvents and then to this polymer dispersion medium, estrogen and various progesterone derivatives were added. The transdermal drug delivery system prolonged the release of these anti-fertility drugs and thus increases their viability for longer time. Mechanism of Action Similar to the combined oral contraceptive, the patch's primary mechanism of action is to prevent ovulation by suppressing gonadotropin secretion. Likewise, it can also thicken the cervical mucus, cause endometrial atrophy and possibly impair tubal transport.
Sector: Pharmaceuticals
Country: India
Area of Application: Pharma industry.
Keywords: drug delivery, transdermal patch.
Advantages: Reduces toxicity and increase patient compliance Requires only weekly administration Avoids the gastrointestinal tract and the "first pass effect" Has almost 100% efficiency in birth control when used properly Can be used in Hormonal Replacement Therapy (HRY) Can be used by women who are unable to take oral medication Continual release gives steady serum hormone levels; no fluctuations Reduction in the appearance of acne, a regular menstrual cycle, decreased PMS symptoms and risk for endometrial and ovarian cancers.
Environmental aspects: Not Applicable
Development Status: Laboratory Model
Legal Protection: Patent in Progress
Technical specifications:
Transfer Terms: Technology Licensing
Target Countries: India
Estimated cost (US$):
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Contact Person: SkyQuest Technology Consulting Pvt. Ltd.
Address: 501, Krishna Complex, Opp. Devashish School, Bodakdev
City: Ahmedabad
Country: India
Zip/Pin Code: 380054