A Novel Composition for Prevention & Treatment of Filariasis
The present invention relates to the synthesis of macrofilaricidal substituted naphthalenediones based upon the lead molecule (5-hydroxy-2-methyl-l, 4-naphthalenedione) obtained from the indigenous medicinal plant Plumbago indica/rosea, which is macrofilaricidally potent. The 5-hydroxy-2-methyl-l,4- naphthalenedione derivatives represented by substituents and C3 positions such as halo, alkyl, aryl, amino, alkylamino, arylamino, alkoxy, aryloxy, amido, carboxylic acid or ester having 1 to 10 carbons. It also describes the process for extraction of macrofilaricidal composition form medicinal plants having one or more derivatives. The extraction of the derivatives is carried out using different alcohol type. A comparative study for the technology was done with DEC which suggest worth of the derivatives, which is 200 times more effective then DEC.
Sector: Pharmaceuticals
Country: India
Area of Application: Medical industry.
Keywords: Filariasis,dielhylcarbamazine citrate
Advantages: 200 times more effective the DEC and other drug Composition inhibits 65 to 90% of parasite. Composition is administered through any of the medically accepted methods. Herbal extract with less side effects. Short and permanent-long term Filariasis in mammals, including humans. More effectively kills adult worms. Huge market.
Environmental aspects: Not Applicable
Development Status: Laboratory Model
Legal Protection: Patent in Progress
Technical specifications:
Transfer Terms: Technology Licensing
Target Countries: India
Estimated cost (US$):
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City: Ahmedabad
Country: India
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