Novel Cancer Detection Techniques
Tumor Antigen Derived Gene (TADG) is a new member of the serine protease family and is a highly overexpressed gene in tumors. The technology offers a screening program to identify proteases, which are overexpressed in carcinoma by examining PCR products amplified using differential display in early stage tumors and metastatic tumors compared to that of normal tissue. TADG protein is composed of multiple domains including a transmembrane domain and several ligand-binding domains with extracellular protease domains at the carboxy terminus. It has potential for targeting tumor cells or for protease inhibition therapy. TADG's ligand-binding domains may be valuable in the uptake of specific molecules into tumor cells.
Sector: Pharmaceuticals
Country: India
Area of Application: techniques,Tumor Antigen
Keywords: techniques
Advantages: Has application as a therapeutic target in both ovarian carcinoma and other cell surface transmembrane protein carcinomas including breast, prostate, lung, and colon Has potential for targeting tumor cells or for protease inhibition therapy
Environmental aspects: Not Applicable
Development Status: Laboratory Model
Legal Protection: Patent
Technical specifications:
Transfer Terms: Technology Licensing
Target Countries: India
Estimated cost (US$):
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Contact Person: SkyQuest Technology Consulting Pvt. Ltd.
Address: 501, Krishna Complex, Opp. Devashish School, Bodakdev
City: Ahmedabad
Country: India
Zip/Pin Code: 380054